水泥混凝土路面的耐久性控制

本文简要论述了影响水泥混凝土耐久性的因素，并讨论了保证水泥混凝土路面耐久性的技术途径及措施。     

传感器输出信号通用线性处理电路的研究

根据电量输出传感器测量物理量的范围,平分二段,分别建立拟合回归方程,并用电路实现之.这种线性处理方法具有通用性.以K型热电偶传感器为实验例子,未经线性处理前,理论线性度为3.2%,线性处理后,理论线性度为0.015%.测量数据标准差为0.00138.结果表明,该方法测量效果良好.     

5G 移动通信技术军事应用研究

为加速推进5G 在军事领域的研究与应用,细化研究方法和实现途径,梳理分析5G 技术发展现状、架构 特点及关键技术。基于多视角梳理分析30 份美国5G 军事应用的政策文件;梳理并评述了国内学术界5G 军事应用 研究的进展和焦点,分析研究特点和短板弱项;提出了5G 军事应用的总体思路和整体框架,并基于“映射法”对 军事应用场景进行量化分析,最后给出建议与展望。结果表明,该研究可为5G 在军事领域的战略顶层设计、应用 优先级设置和建设研究实践提供参考。     

One‐Pot Synthesis of Dealloyed AuNi Nanodendrite as a Bifunctional Electrocatalyst for Oxygen Reduction and Borohydride Oxidation Reaction

A novel one‐pot approach for synthesizing the dealloyed nanomaterials at room temperature is introduced for the first time. In such a synthetic strategy, applying modulated potentials effectively simplifies the traditional dealloying route, which usually requires additional corrosion process to dissolve nonprecious metals. The dealloyed AuNi nanodendrites (AuNi NDs) with tunable composition and uniformly elemental distribution are well developed by the one‐pot strategy. Impressively, the as‐synthesized AuNi NDs exhibit a higher electrochemically active area and definite improvements in electrocatalytic activity for oxygen reduction reaction (ORR) and borohydride oxidation reaction (BOR) compared to the commercial Pt/C. In particular, the AuNi NDs are 81 mV more positive in half‐wave potential and about 3.1 times higher in specific activity (at 0.85 V) for the ORR than Pt/C, together with excellent stability and methanol tolerance. The superior BOR activity is highly promising compared to the previously reported catalysts. The unique nanodendritic structure with Au‐rich surface and bimetallic electronic effect is the main factor to greatly enhance the bifunctional catalytic performance for the AuNi NDs. Furthermore, such a newly developed facile method is of great significance because it is one of the first examples to effectively engineer dealloyed bimetallic nanostructures via the practical and low‐cost route for electrocatalytic applications.     

Identification and characterization of solids in sand-water two-phase flows via vibration multi-sensor approaches

The monitoring of tiny particles in multiphase pipe flow is widely encountered in industry. In this paper, the identification and characterization of solid particles suspended in sand-water flow were developed based on vibration multi-sensor approaches. Verification experiments were conducted, and good agreement was found between the concentrations (0–0.1 wt% with an interval of 0.02 wt%) of varisized sands (from 86 to 180 μm) and the monitored vibration signal characteristics by multi-sensor approaches. A quadratic relationship between the particle concentration and vibration energy was obtained. In sand-carrying flow measurement experiments, the sand’s characteristic frequency bands were found at 22–23.6 kHz and 24.8–26.6 kHz. Additionally, the sand particle identification effect was evaluated from two positions at bends, that is, the outer wall of the 45-degree bend on the elbow and the exit of the 90-degree bend. Compared with these two monitor positions, the sand vibration energy from the outlet of the elbow had a higher signal-to-noise ratio with obvious energy variations. In addition, the accuracies of the detected sand vibration features were mutual confirmation. Consequently, the above methods are applicable for little solid detection in sand-water flow, which lays the foundation for particles monitoring in the complexed multiphase flow.     

药物免修饰的药靶鉴定蛋白质组方法研究进展

药物靶蛋白的筛选是现代药物研发过程必不可少的步骤。传统的药物靶点筛选通常使用假设驱动的生物学实验进行药物靶点的逐个验证，近年来高通量、高分辨质谱技术的进步以及液相色谱-质谱联用技术的发展，促进了蛋白质组学技术在药物靶蛋白筛选领域的广泛应用。化学蛋白质组学技术在药物-蛋白相互作用研究领域已取得巨大突破，因其需要在药物小分子结构上进行化学衍生等问题，最近新兴的药物免修饰的靶蛋白筛选技术引起广泛关注。本文综述了近15年来药物免修饰（非化学修饰）的药物靶蛋白筛选方法的研究进展，包括细胞热位移分析（CETSA）、热蛋白质组分析（TPP）、蛋白质氧化速率稳定性分析（SPROX）、基于有机溶剂沉淀蛋白稳定性方法（SIP）、药物亲和相应靶点稳定性分析（DARTS）、脉冲酶解法（PP）、限制性酶解法（LiP）等，并比较了这些方法的优势、局限性以及应用场景。     

Strategies to Modulate Specialized Metabolism in Mediterranean Crops: From Molecular Aspects to Field

Plant specialized metabolites (SMs) play an important role in the interaction with the environment and are part of the plant defense response. These natural products are volatile, semi-volatile and non-volatile compounds produced from common building blocks deriving from primary metabolic pathways and rapidly evolved to allow a better adaptation of plants to environmental cues. Specialized metabolites include terpenes, flavonoids, alkaloids, glucosinolates, tannins, resins, etc. that can be used as phytochemicals, food additives, flavoring agents and pharmaceutical compounds. This review will be focused on Mediterranean crop plants as a source of SMs, with a special attention on the strategies that can be used to modulate their production, including abiotic stresses, interaction with beneficial soil microorganisms and novel genetic approaches.     

Data driven nonparametric identification and model based control of glucose-insulin process in type 1 diabetics

Closed loop control of glucose homeostasis via subcutaneous insulin infusion and continuous glucose monitoring system can give better living to a type 1 diabetic patient. This paper deals with the real time implementation of internal model control (IMC) of subcutaneous insulin infusion. The model based control is applied on the nonparametric model of the patient identified in real time from input–output data. Meal simulation model of the glucose-insulin system of type 1 diabetic patient based on the work of Dalla Man et. al. is considered. This model is constructed in hardware platform that acts as the virtual patient. The data-driven nonparametric model of the virtual patient is identified in real time by computing Volterra kernels. The kernels are solved up to second order using recursive least squares (RLS) algorithm with short memory length of M = 2. The validation results of the identified model output and the actual output have shown good fit in both simulation and real time environments. The frequency domain kernels are used in internal model control to generate insulin dosage. The control algorithm is developed in simulation and implemented in real time with hardware in loop on dSPACE platform. The closed loop system yields good meal disturbance rejection, less undershoots, settling time and more profoundly smaller requirement of insulin infusion as compared to the earlier reported data.     

文档加密技术在企业数据安全方面的应用

数据安全是保证工程技术公司正常运转的关键。以某公司为例,介绍了DGS文档加密系统的基本架构和特点,以及该加密系统的具体实施及功能实现,并提出了该系统目前仍存在的一些问题。     

Viewpoint: Information systems research strategy

This article^1,2 has two aligned aims: (i) to espouse the value of a strategic research orientation for the Information Systems Discipline; and (ii) to facilitate such a strategic orientation by recognising the value of programmatic research and promoting the publication of such work. It commences from the viewpoint that Information Systems (IS) research benefits from being strategic at every level, from individual researcher, to research program, to research discipline and beyond. It particularly advocates for more coordinated programs of research emphasising real-world impact, while recognising that vibrant, individual-driven and small-team research within broad areas of promise, is expected to continue forming the core of the IS research ecosystem. Thus, the overarching aim is the amplification of strategic thinking in IS research – the further leveraging of an orientation natural to the JSIS community, with emphasis on research programs as a main strategic lever, and further considering how JSIS can be instrumental in this aim.